TrumpRx Launches: What This New Prescription Drug Website Means for Your Health Coverage | RKA
President Trump launched TrumpRx.gov—a direct-to-consumer website offering discounted prescription drugs including Ozempic, Wegovy, and Zepbound. Discounts apply to cash-paying patients only and do NOT work with insurance. Here's who benefits, how it affects your coverage decisions, and what it doesn't cover.
TrumpRx Launches: What This New Prescription Drug Website Means for Your Health Coverage
Fast take: President Trump launched TrumpRx.gov on February 5, 2026—a direct-to-consumer website offering discounted prescription drugs at "most favored nation" prices. The discounts apply to cash-paying patients only and do not work with insurance. Here's what you need to know and how it affects your coverage decisions.
Not sure if TrumpRx or insurance is the better deal for your prescriptions?
We'll compare your total costs—premiums, deductibles, and Rx—across ACA Marketplace plans, private PPOs, and cash-pay options like TrumpRx.
Get Free Quotes Book a CallWhat is TrumpRx?
TrumpRx.gov is a new government website that connects patients directly to pharmaceutical companies offering discounted prescription drugs. It launched with 43 brand-name medications from five manufacturers: AstraZeneca, Eli Lilly, EMD Serono, Novo Nordisk, and Pfizer. More drugs from 16 total participating manufacturers are expected to be added.
The site doesn't sell drugs directly. Instead, it provides coupons you can print or download to your phone and present at your pharmacy, or it directs you to manufacturer websites like LillyDirect or NovoCare to complete your purchase.
Key drugs and new prices
Weight Loss / Diabetes
Ozempic: $1,028 → $350/month
Wegovy (injectable): $1,349 → as low as $199/month
Wegovy (pill): $1,349 → as low as $149/month
Zepbound: $1,088 → as low as $299/month
Fertility Medications
Gonal-F: as low as $168/pen
Cetrotide: $316 → $22.50
Ovidrel: $251 → $84
Potential savings: $2,000+ per fertility cycle
Respiratory
Bevespi Aerosphere (COPD): $458 → $51
Airsupra (asthma): $504 → $201
Other Medications
Eucrisa (dermatitis): $792 → $158
Insulin Lispro: as low as $25/month
Duavee (menopause): $202 → $30
Who benefits most from TrumpRx?
TrumpRx may help if you...
✓ Are uninsured and pay cash for prescriptions
✓ Need GLP-1 drugs (Ozempic, Wegovy, Zepbound) not covered by your insurance
✓ Pay for fertility treatments out-of-pocket
✓ Have high-deductible plans and haven't met your deductible
✓ Take brand-name drugs with no generic alternative
TrumpRx probably won't help if you...
✗ Have insurance with reasonable copays
✗ Take generic medications (9 in 10 prescriptions are generics)
✗ Have already met your deductible for the year
✗ Want purchases to count toward your out-of-pocket max
✗ Need drugs not listed on the platform
⚠️ Important: TrumpRx Does NOT Work With Insurance
TrumpRx discounts are for cash-paying patients only. If you use TrumpRx:
✗ You cannot use your insurance
✗ Purchases do NOT count toward your deductible
✗ Purchases do NOT count toward your out-of-pocket maximum
For many people with insurance, using your plan's pharmacy benefit will cost less over the course of the year.
How TrumpRx affects your health insurance decision
TrumpRx doesn't replace health insurance—it's a prescription discount program. But it does change the math for some people when comparing coverage options:
If you need GLP-1 drugs
Weight loss medications like Wegovy and Zepbound are often excluded from insurance plans. TrumpRx pricing ($149-$350/month) may now make these accessible without needing a plan that covers them—which expands your insurance options.
If you're comparing high-deductible vs. low-deductible plans
A high-deductible plan with lower premiums + TrumpRx for specific brand-name drugs might cost less annually than a low-deductible plan. We can model both scenarios for you.
If you're self-employed with variable income
For some self-employed individuals, a catastrophic or high-deductible plan + cash-pay options like TrumpRx + an HSA may provide better value than a comprehensive plan with high premiums.
If you're uninsured
TrumpRx helps with specific brand-name drugs, but it's not a substitute for major medical coverage. You still need insurance for hospitalizations, surgeries, preventive care, and most prescriptions.
What TrumpRx does NOT cover
✗ Generic medications (90% of all prescriptions)
✗ Doctor visits and preventive care
✗ Hospitalizations and surgeries
✗ Emergency room visits
✗ Lab work and imaging
✗ Most brand-name drugs (only 43 currently listed)
The bottom line
TrumpRx is a useful tool for specific situations—especially for uninsured patients or those needing expensive brand-name drugs not covered by their insurance. But for most people with health coverage, your insurance pharmacy benefit will still be the better deal over the course of the year.
The real question is: How does this fit into your total healthcare cost picture? That depends on your income, health status, prescription needs, and which plans are available in your state.
Need help comparing your total costs?
We'll model premiums + deductibles + prescriptions across ACA plans, private PPOs, and cash-pay options to find what actually costs you less.
Get Free Quotes Book a CallQuick FAQs
Can I use TrumpRx with my insurance?
No. TrumpRx discounts are only for cash-paying patients. If you use TrumpRx, you cannot bill your insurance for that purchase, and it won't count toward your deductible or out-of-pocket maximum.
Is TrumpRx cheaper than my insurance copay?
It depends on your plan. For many people with insurance, copays are lower than TrumpRx prices—especially after meeting your deductible. Compare both options before deciding.
Does TrumpRx replace health insurance?
No. TrumpRx only covers 43 specific brand-name drugs. You still need health insurance for doctor visits, hospitalizations, preventive care, generic medications, and most prescriptions.
How do I use TrumpRx?
Visit TrumpRx.gov, find your medication, and either print a coupon to take to your pharmacy or complete your order through the manufacturer's website (like LillyDirect or NovoCare).
What about generic drugs?
TrumpRx only offers brand-name drugs. For generics (which account for 90% of prescriptions), sites like Mark Cuban's Cost Plus Drugs or your insurance pharmacy benefit are typically better options.
For education only; pricing and availability subject to change. Always compare options before purchasing medications. This is not medical advice—consult your healthcare provider about treatment decisions.